KMID : 0359020110420040222
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Korean Journal of Gastrointestinal Endoscopy 2011 Volume.42 No. 4 p.222 ~ p.227
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Treatment Outcomes after Endoscopic Submucosal Dissection of Large Superficial Rectosigmoid Colon Tumors
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Koh Jin-Sung
Park Jong-Jae Chung Won-Ho Lee Joon-Young Lim Sang-Ah Kwon Min-Jung Noh Hye-jin Joo Moon-Kyung Lee Beom-Jae Kim Ji-Hoon Yeon Jong-Eun Kim Jae-Seon Byun Kwan-Soo Park Young-Tae
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Abstract
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Background/Aims :Endoscopic submucosal dissection (ESD) of a colorectal tumor is technically difficult. This study aimed to analyze the clinical outcomes of superficial large rectosigmoid tumors after ESD.
Methods:Medical records of 15 patients with large rectosigmoid tumors (more than 30 mm), in which ESD performed, were reviewed retrospectively.
Results:The mean tumor size was 42.5¡¾14.3 mm (range, 30¡78 mm). A histological examination revealed awell-differentiated adenocarcinoma in five cases (33.3%), adenoma with high-grade dysplasia in six cases (40%), and low-grade dysplasia in four cases (26.7%). The mean procedural time was 90.5¡¾60.7 min (range, 22¡246 min). The en bloc resection rate was 86.7%, and the complete resection rate 100%. The lateral resection margin was positive in four cases (26.6%), but no cases with a positive vertical margin were observed. Bleeding occurred in three cases (20%), and all were treated successfully using endoscopic measures. Perforations occurred in three cases (20%); two cases were treated by clipping and the other by a laparotomy.
Conclusions:ESD is a treatment option for superficial large rectosigmoid tumors. Further studies with larger cases and a longer term follow-up are needed to establish the efficacy and safety of ESD for colorectal tumors.
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KEYWORD
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Endoscopic submucosal dissection, Large superficial tumor, Rectosigmoid colon, Outcomes
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